![]() This judgment prompted a decision to convert the breeding contract at the CPRC to a grant that combined production breeding with a research program focused on better understanding the biology of Saimiri. It was determined that the body of knowledge of the basic biology (more specifically reproductive biology) of squirrel monkeys was not adequate to resolve the difficulties in captive breeding. Other facilities breeding squirrel monkeys also reported less successful reproduction than that of other commonly used nonhuman primates ( Johnsen and Whitehair 1986 ). By 1979, production at the CPRC remained far below expectations, prompting a review of reproduction methods in this genus. A production breeding contract was awarded in 1975 to the Caribbean Primate Research Center (CPRC 1 ) to meet the need for squirrel monkeys in NIH-sponsored research. The National Heart Institute’s support for this breeding colony was subsequently ended.īy 1975, the Animal Resources Branch (now the Comparative Medicine Area) of the Division of Research Resources (now the National Center for Research Resources) of the National Institutes of Health (NIH 1 ) had recognized the importance of the squirrel monkey in a number of biomedical research areas. Of 41 term pregnancies, 22 resulted in living births (with five subsequent deaths) and 17 were stillbirths or abortions. ![]() During the next 10 yr, Goss and coworkers learned that squirrel monkeys adapted well to laboratory conditions and were easy to handle however, their reproduction was poor. In 1947, the first births in captivity were reported ( Klüver and Brunschwig 1947 ) and 2 yr later, the National Heart Institute awarded the first grant to establish a breeding colony of squirrel monkeys to the Anatomy Department of the Louisiana State University School of Medicine ( Goss et al. The early work of Klüver at the University of Chicago provided the first description of housing methods and experimental use of squirrel monkeys. The first reports of the use of squirrel monkeys in research were published about 65 yr ago ( Klüver 1933 ). ![]()
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